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• ACF Funded Training, Assessment, and Treatment Program
• SAMHSA funded Trauma Treatment Program
• CDC funded Neuro- cognitive Habilitation program
• HRSA funded FASD training program
• Donor funded Infant Development Study
• Research Publications

Research at CRT

Children's Research Triangle's Research Department has been in the forefront of many issues related to maternal substance abuse in pregnancy, the outcomes of children prenatally exposed to drugs, and the child welfare implications of substance abuse in families. The staff at CRT has written articles that have been published in Pediatrics, The New England Journal of Medicine, The Journal of Pediatrics, The Journal of the American College of Obstetrics and Gynecology, the Journal of the American Medical Association, and numerous other leading medical journals.

Children's Research Triangle's clinical research team has led and participated in a number of federally funded research studies that have changed the practice of health and behavioral health care for women and children:

• From April 1986 through March 1993, Dr. Chasnoff and his research team studied the impact of cocaine use in pregnancy on pregnancy outcome and the long term development of the exposed child. From this study came the first description of the effects of prenatal cocaine exposure on children. (Funded by the National Institute on Drug Abuse, National Institutes of Health and the US Department of Education)
• The research team established the standard for gender-specific treatment of pregnant women through a randomized study (1989--1994) of outpatient vs. residential care for polydrug using pregnant women. (Funded by the National Institute on Drug Abuse, National Institutes of Health)
• Prevention of substance abuse and violence among school children was the focus of a study based in several schools around the nation, conducted from 1996 through 1998. (Funded by the US Department of Education)
• CRT's first studies to investigate the relationship between substance abuse in families and the child welfare system were conducted from 1997 through 2001. (Funded by Substance Abuse and Mental Health Services Administration/US Department of Health and Human Services)
• CRT, in its partnership with NTI Upstream, has developed strategies for screening pregnant women for substance abuse, domestic violence, and depression. In 1990 through 1992, CRT conducted the first studies to identify the factors that predict a woman's risk for substance abuse. This was followed by a series of studies to determine clinical approaches that would motivate providers to conduct screening in the prenatal care setting (1999--2005) and a large study to expand screening from substance abuse alone to include assessing risk for domestic violence and depression (2003--2006). (Funded by the Health Care Financing Authority/US Department of Health and Human Services and the Maternal Child Health Bureau/Health Resources and Services Administration)
• CRT, in a partnership with Kaiser Permanente in Oakland, California, is conducting a validation study of the 4 P's Plus © screen. (Funded by the National Institute on Alcohol Abuse and Alcoholism/National Institutes of Health)
• CRT's efforts to develop treatment for adolescents with FAS/ARND have been led through a research study of appropriate strategies for addressing the needs of these high risk youth. (Funded by Substance Abuse and Mental Health Services Administration/US Department of Health and Human Services)
• From 2001-2005, CRT was funded to develop and evaluate an intervention strategy for treating 6 to 12 year old children with FAS or ARND. CDC extended the funding through 2009 to replicate the study in a rural area of Illinois. (Funded by the Centers for Disease Control and Prevention/ US Department of Health and Human Services)
• CRT is funded to develop a training and technical assistance program for Community Health Centers and Maternal and Child Health sites across the nation. This project is designed to integrate substance abuse screening into primary prenatal health care settings. In addition, pediatricians are screening for FASDs in their primary health care settings. (Funded by the Maternal Child Health Bureau/Health Resources and Services Administration)
• CRT is in the second year of developing an interactional parent/child intervention for preschool children who are experiencing relational, developmental and/or behavioral difficulties. (Funded by the Michael Reese Health Trust)